منابع مشابه
An efficient algorithm for minimal primer set selection
SUMMARY We have developed U-PRIMER, a primer design program, to compute a minimal primer set (MPS) for any given set of DNA sequences. The U-PRIMER algorithm, which uses automatic variable fixing and automatic redundant constraint elimination to tackle the binary integer programming problem associated with the MPS selection problem. The program has been tested successfully with 32 adipocyte dev...
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UNLABELLED G-PRIMER, a web-based primer design program, has been developed to compute a minimal primer set specifically annealed to all the open reading frames in a given microbial genome. This program has been successfully used in the microarray experiment for analyzing the expression of genes in the Xanthomonas campestris genome. AVAILABILITY It is available at http://mammoth.bii.a-star.edu...
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An efficient cluster head selection algorithm in wireless sensor networks is proposed in this paper. The implementation of the proposed algorithm can improve energy which allows the structured representation of a network topology. According to the residual energy, number of the neighbors, and the centrality of each node, the algorithm uses Fuzzy Inference Systems to select cluster head. The alg...
متن کاملAn Iterative Beam Search Algorithm for Degenerate Primer Selection
AN ITERATIVE BEAM SEARCH ALGORITHM FOR DEGENERATE PRIMER SELECTION by Richard M. Souvenir ADVISOR: Professor W. Zhang December, 2003 Saint Louis, Missouri Single Nucleotide Polymorphism (SNP) Genotyping is an important molecular genetics process in the early stages of producing results that will be useful in the medical field. Due to inherent complexities in DNA manipulation and analysis, many ...
متن کاملPrimer Set Selection in Multiple PCR Experiments
The selection of a suitable set of primers is crucial to the multiple PCR (polymerase chain reaction) experiment, which is one of the most important techniques in molecular biology. The minimum primer set (MPS) problem is to minimize the number of primers required to amplify a set of DNA sequences, so that the experimental costs and time will be reduced. However, the MPS problem has been proved...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2003
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/19.2.285